Charge transfer complexes were attended by the interaction of Schiff base (amlodipine + Picolin aldehyde) with 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) to create a Compound that produced the maximum absorption at a wavelength of 436 nm by selecting the optimal conditions for the interaction between the two compounds which were adopted in subsequent experiments. The study covers the development of a straightforward and precise spectrophotometry for the measurement of amlodipine (AML) in pharmaceutical formulations and pure forms. The molar absorption rate was 1.4556×104 l.mol-1.cm-1, the correlation coefficient was 0.9981, the sandal sensitivity was 0.0281.µg.cm-2, And the Beer's law limit was 5–40 µg.ml1. When this technique was used to estimate the amount of AML in pharmaceuticals, the composition of the resultant compound revealed that the detection limit (0.2596 µg.ml-1). The quantitative limit (0.7865µg.ml-1), and the Rec value (%103.1124-96.8260) were all within the range of 0.2257-0.6258. Additionally, AML measurement approach has proven effectively. Characterized complexes by U.V, FTIR and Spectrum of Mass.
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