Digital Evaluation of Physiological, Histological, and Immunological Effects of Lambda-Cyhalothrin Exposure in Male Albino Rats

Al-Swefee, Duha; AL-Chalabi, Ahmed

doi:10.25673/123574

Proceedings of International Conference on Applied Innovation in IT · 2026/03/31 · Vol. 14 · Issue 1 · pp. 323–329

Digital Evaluation of Physiological, Histological, and Immunological Effects of Lambda-Cyhalothrin Exposure in Male Albino Rats

Duha Zeki Al-Swefee, Ahmed Saleem AL-Jumaili and Salah Mahdi Muhsin AL-Chalabi

📄 Download PDF DOI: 10.25673/123574

Abstract

Pesticides primarily act to get rid of the harmful effects caused by rodents, insects, weeds, and others. This study aimed to investigate the adverse effects of varying lambda-cyhalothrin pesticide concentrations on several physiological, histological, and immunological parameters in male rats, including lipid profiles, liver and kidney functions, and Tumor Necrosis Factor Alpha, Lactate Dehydrogenase, and C-Reactive Protein levels. This study included 15 male albino rats, weighing 180-190g and 5-6 months of age, separated into the following three groups: group 1 was considered a control group and was given only water and food. The 2nd and 3rd groups were administered pesticides at concentrations of 15 and 30 mg/kg, respectively. The animals were orally administered 15 and 30 mg/kg pesticides for 30 days. The data revealed a significant increase in cholesterol, triglycerides, Low Density Lipoprotein, Very Low-Density Lipoprotein, Alanine Transaminase, Aspartate transaminase, and blood urea. creatinine, Tumor Necrosis Factor Alpha, Lactate Dehydrogenase, C-Reactive Protein, and a significant decrease in High Density Lipoprotein in the treated group with the two concentrations of pesticide compared with the control group. Liver and kidney tissue sections were taken as biomarkers for histopathological alterations after exposure to Lambda-Cyhalothrin pesticide. All findings in this study were digitally documented to ensure accurate recording and presentation of the physiological, histological, and immunological results.

Keywords

Lambda-Cyhalothrin TNF-Α Immunological Biomarker Liver Kidney Albino Rats.

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